Conferences 2007 Fort Lauderdale Eighth International Conference Agenda-Professional

Friday, January 12th

7:00am                 
Registration Opens


8:00-8:10am        
Welcome & Introduction                              
Nancy Klimas, M.D.
President, IACFS
Faculty, Dept. of Medicine,
University of Miami School of Medicine

Marly C.  Silverman
Founder, Patient Alliance for
Neuroendocrineimmune Disorders
Organization for Research and
Advocacy (P.A.N.D.O.R.A.)


Fatigue Session                                                                     
Session Chair: Nancy Klimas, M.D.
Session Description: Interdisciplinary session: 
Lessons learned in other fatiguing illnesses;
Immune/neuro/endocrine interactions;
cellular mechanisms; interventions.

8:10-8:40am        
Introductory Overview                                       
Professor Yasuyoshi Watanabe
Osaka City Medical School, Osaka, Japan

8:40-10:15am     
Fatigue Paper Presentations           

Estimation of fatigue state in patients with chronic fatigue syndrome
 using Actigraphy and R-R interval power spectrum analysis
Seiki Tajima, M.D.

Examining and Distinguishing Types of Fatigue
Nicole S. Porter, Ph.D.

CFS is Associated with High Allostatic Load in Georgia
Elizabeth M. Maloney, DrPH, M.S.

Chronic Fatigue Syndrome and the Abnormal Exercise Stress Test
Margaret Ciccolella, J.D., Ed.D.

â-Alanine and g-Aminobutyric Acid in Chronic Fatigue Syndrome
Ulf Hannestad, MSc.

A Comparison of Neurometabolites in  Chronic Fatigue Syndrome,
Generalized Anxiety Disorder, and Healthy Volunteers
Paul S. Nestadt, B.S.

Alterations in Apoptosis Play a Role in Post-Infection Fatigue
Toni Whistler, Ph.D.

10:15-10:45am   
Fatigue Session Summary: State-of-the-Art with a CFS-Perspective     
Fred Friedberg, Ph.D., IACFS Board Member
Principal Investigator, Chronic Fatigue Syndrome Research Project,
Stony Brook University, Stony Brook, NY


10:45-11:00am   
Break - Visit Exhibits


Sleep Session                                    
Session Chair: Birgitta Evengard, M.D., Ph.D.
Session Description:  Interdisciplinary session:
Sleep in other chronic illnesses; impact of sleep
cycle on function; neuro/ immune/endocrine
interactions; animal models; interventions                    
                                                                               
11:00-11:30am   
Introductory Overview                                       
Joan L. Shaver, Ph.D., R.N., FAAN
Professor & Dean, University of Illinois at
Chicago (UIC), College of Nursing

11:30-12:00pm   
Sleep Session Summary: State-of-the-Art with a CFS Perspective                         
Charles Lapp, M.D., IACFS Board Member
Private Practice Clinician, Raleigh, NC
Clinical Professor, Duke University


12:00-12:55pm   
Lunch - Visit Exhibits & Posters


12:15-12:45pm   
Lunch Workshop- CFS Research Funding                
                               
Nancy Klimas, M.D.
President, IACFS
Faculty, Dept. of Medicine,
University of Miami School of Medicine

Eleanor Z. Hanna, Ph.D.
Associate Director for Special Projects and Centers, Office of Research on
Women’s Health, Office of the Director, National Institutes of Health

Kimberly McCleary
President & Chief Executive Officer,
CFIDS Association of America

Patricia D. Fero, MEPD
Executive Director, Wisconsin CFS Association


 

Clinical Trials Session
Session Co-Chairs: Barry Hurwitz, Ph.D.
                                    Jose G. Montoya, M.D.
Session Description: Discussion of three specific on-going clinical
                                    trials for CFS intervention.

12:55-1:00pm
Introductory Overview
Barry Hurwitz, Ph.D.

1:00-1:15pm
Clinical Trials Paper Presentation
Therapeutic Effect of Epoetin Alpha on Red Blood Cell Volume, Perceived Fatigue
and Susceptibility to Syncope in Chronic Fatigue Syndrome:  Miami Epoetin
AlphaClinical Trial
Barry Hurwitz, Ph.D.

1:15-1:30pm
Use of Valganciclovir (VGCV) in Patients with High Antibody Titers Against Human
 Herpes Virus 6 (HHV-6) and Epstein-Barr Virus (EBV) who were Experiencing Virus
Induced Fatigue with CNS Dysfunction (VIFCD)
Jose G. Montoya, M.D.

1:30-1:45pm
Phase I Clinical Trial of Valacyclovir in the Epstein-Barr Virus Subset of
Chronic Fatigue Syndrome
A. Martin Lerner, M.D.


               
Pain Session                                                              
Session Chair: Lucinda Bateman, M.D.
Session Description: Mechanisms of pain in chronic illness;
influence of inflammation; central and peripheral pain mechanisms; interventions
                                                                                               
1:45-2:10pm        
Introductory Overview: A Life of Pelvic Pain                               
Karen J. Berkley, Ph.D.
McKenzie and Distinguished Research Professor,
Program in Neuroscience, Florida State University

2:10-2:25pm        
Pain Paper Presentations

Inflammation and Arterial Stiffness in Patients with Chronic Fatigue Syndrome
Vance A. Spence, Ph.D.

Chronic widespread pain and its comorbidities: A population-based study
Kenji Kato, Ph.D.
                                                                                               
2:25-2:45pm        
Pain Session Summary: State-of-the-Art with a CFS Perspective
Dan Clauw, M.D.


2:45-3:00pm        
Break - Visit Poster Presentations & Exhibits


Epidemiology & Case Definition Session
Session Co-Chairs: William C. Reeves, M.D.
                                 Eleanor Z. Hanna, Ph.D.
Session Description: Prevalence, incidence,
illness trajectory, impact on research priorities

3:00-3:25pm        
Introductory Overview       
Richard Herrell, Ph.D.
NIMH,Washington, D.C.

3:25-3:35pm
Epidemiology Case Definition Paper Presentation
Subgroups of Chronic Fatigue Syndrome in Metropolitan, Urban, and Rural Georgia
William C. Reeves, M.D.

3:35-3:55pm
Epidemiology Case Definition Panel Discussion 
Moderator: Eleanor Z. Hanna, Ph.D.

Panel:
William C. Reeves, M.D.
Leonard Jason, Ph.D.
James F. Jones, M.D.

3:55-4:45pm        
Epidemiology Paper Presentations

Change in Chronic Fatigue Symptom-Complex: 10-Year Interval Post
Gulf War Deployment
Han K. Kang, Dr. P.H.

Chronic Fatigue Syndrome in the Offspring of Mothers with CFS
Rosemary A. Underhill, MB, BS, FRCSE, MRCOG

Preliminary observations from a case-control study on chronic fatigue syndrome
in monozygotic Swedish Twins
Andreas Jacks, M.D.

Unidentified somatic complaints following 9/11: More than depression?
Barbara G. Melamed, Ph.D., ABPP

The Economic Impact of Chronic Fatigue Syndrome in a Community-Based Versus
a Tertiary Sample
Leonard Jason, Ph.D.

4:45-5:00 pm       
Epidemiology Session Summary: State-of-the-Art with a CFS-Perspective
Leonard A. Jason, Ph.D., Vice President, IACFS
Center for Community Research, DePaul University, Chicago, IL


International CFS Forum

Session Chair: Hirohiko Kuratsune, M.D., D.Med.Sci.
Session Description: Short Oral Presentations and Panel Discussion on
International Health with representatives from across the globe discussing research
directions and clinical approaches.

5:00-5:20pm
International CFS Forum Paper Presentations

Chronic Fatigue Syndrome in Developing Countries: The Nigerian Case
Leonard A. Jason, Ph.D.

Chronic Fatigue Syndrome in Iceland
Eirikur Lindal, Ph.D.

5:20-6:00pm
Panel Discussion
Moderator: Hirohiko Kuratsune, MD, D.Med.Sci.
IACFS Board Member
Director, Japanese Study Group for Chronic Fatigue Syndrome in
Ministry of Education, Science, Sports and Culture Assistant Professor,
Osaka University Graduate School of Medicine, Osaka, Japan

Panel:
Birgitta Evengard, M.D., Ph.D.,Board Member, IACFS
Chairman Conference Planning Committee, IACFS
Senior Doctor & Professor, Karolinska University Hospital, Stockholm, Sweden

Kenny De Meirleir, M.D., Ph.D., Board Member, IACFS
Professor of Physiology, Pathophysiology and Medicine,
Vrije Universiteit, Brussels Belgium

Nancy Klimas, M.D., President, IACFS
Faculty, Dept. of Medicine,
University of Miami School of Medicine

Marcia Harmon
CFIDS Association of America

Umberto Tirelli, M.D.
Director, Department of Medical Oncology, National Cancer Institute, Aviano, Italy

Rosamund Vallings, MB, BS
Advisor, New Zealand ME/CFS Association
Editorial Board, International Journal of Chronic Fatigue Syndrome


6:00 pm
Registration Closes


6:00-7:00pm        
IACFS Membership Meeting
 

Saturday, January 13th

8:00am 

Registration Opens


 

Brain Function Session
Session Chair: Patricia Fennell, MSW, LCSW-R
Session Description: Mechanisms of brain dysfunction;
what can be learned from imaging; clinical assessment of
cognition and mental fatigue; clinical interventions

8:00-8:30am        
Introductory Overview
Gudrun Lange, Ph.D., IACFS Board Member
Professor ,UMDNJ-New Jersey Medical School, Director,
VA War Related Illness and Injury Study Centers

8:30-9:30am        
Brain Function Paper Presentations

Brain SPECT Quantification in Chronic Fatigue Syndrome
Profesor J.  Alegre-Martín

Brain SPECT Quantification in Chronic Fatigue Syndrome: Comparison of Basal and Post-Stress Studies
Profesor J.  Alegre-Martín

Assessment of Information Processing in Chronic Fatigue Syndrome
Fumiharu Togo, Ph.D.

Using a Reaction Time Paradigm to Assess Neurocognitive Function in CFS
Christopher R. Snell, Ph.D.
Defining Occupational Disability in Patients suffering from Chronic Fatigue Syndrome
Elke L.S. Van Hoof, Ph.D.

9:30-10:00am
Session Summary: State-of-the-Art with a CFS-Perspective
Hirohiko Kuratsune, M.D.,D.Med.Sci.,
Dept. of Molecular Medicine, Hematology, and Oncology Osaka
University Graduate School of Medicine, Osaka, Japan


10:00-10:30am   
Break -Visit Poster Presentations & Exhibits


Behavioral Health Session
Session Chair:Fred Friedberg, Ph.D.
Session Description Interdisciplinary session: 
psychoneuroimmunology and health, Coping with chronic illness, treatment

10:30-11:00am
Introductory Overview
Eleanor Stein, M.D., FRCP(C)
Private Practice Psychiatric Care, Calgary, Canada

11:00-11:30am
Behavioral Health Paper Presentations

Exercise Improves Fatigue in Women with Fibromyalgia:
Results of a Randomized Clinical Trial
Deborah Da Costa, Ph.D.

Changing Attitudes toward Chronic Fatigue Syndrome:
 A Pilot Study in Fourth Year Medical Students
Fred Friedberg, Ph.D.

11:30-12:00pm
Session Summary: Behavioral Health with a CFS-Perspective

Patricia A. Fennell, MSW, LCSW-R, IACFS Board Member

President/CEO, Albany Health Management Associates


12:00-1:00pm
Lunch - Visit Poster Presentations & Exhibits


12:15-12:45pm
Lunch Workshop: Success in Clinical Practice,
How to Manage a Successful Practice

Charles Lapp, M.D., IACFS Board Member
Private Practice Clinician, Raleigh, NC
Clinical Professor, Duke University

Marly C.  Silverman
Founder, Patient Alliance for Neuroendocrineimmune
Disorders Organization for Research and Advocacy
(P.A.N.D.O.R.A.)


Pediatrics Session
Session Chair: Leonard A. Jason, Ph.D.

1:00-1:30pm
New Pediatric Case Definition for CFS
Leonard A. Jason, Ph.D., Vice President, IACFS
Center for Community Research, DePaul University
Chicago, IL

David Bell, M.D., IACFS Board Member
Chairman, CFS Advisory Committee of the Department of Health
and Human Services, Associate Clinical Professor, Department of Pediatrics,
University of NY at Buffalo

1:30-2:00pm
Case Studies / Panel Discussion
Leonard A. Jason, Ph.D., David S. Bell, M.D.
Katherine S. Rowe, M.D.
Elke L.S. Van Hoof, Ph.D.
Charles Lapp, M.D.
Alan Gurwitt, M.D.
Teruhisa Miike, M.D., Ph.D.
Susan Torres-Harding, Ph.D.
Kenny De Meirleir, M.D.

2:00-2:30pm
Pediatric Data Pieces

Dysmenorrhoea and exacerbation of CFS symptoms
Katherine S. Rowe, M.D.

How do adolescents with chronic fatigue syndrome perceive their
 social environment? A quantitative study
Elke L.S. Van Hoof, Ph.D.

Pilot Study: Education and Strategies to Help Adolescents with CFS
(and their families) Cope with CFS
Constance W. Van der Eb, Ph.D.


2:30-3:30pm
Poster Presentation Session (Selected Oral Presentations)

Chair: Fred Friedberg, Ph.D.
Session Description: The IACFS Planning Committee selected
several outstanding poster presentations and provided authors with
an opportunity to give a short oral presentation during this session.

Behavioral Section

Computer-assisted cognitive function assessment in fibromyalgia, chronic fatigue syndrome and multiple chemical sensitivity patients
Dr. Ferran J. García-Fructuoso

A Qualitative analysis of the experience and influence of low intensive interval training in women  with Chronic Fatigue Syndrome
Claudia Lennartsson, MSc

A Chronic Fatigue Syndrome Health Behavior and Education Train-the-Trainer Program for Primary Care Providers
Dana Jones Benet, PhD, MPH

Using Comprehensive Clinical Case Management to Improve Health-Care Utilization and Coping in Patients and Families Affected by CFS/FM
Patricia Fennell, MSW, LCSW-R

 

Brain Function Section

Autonomic, metabolic and immune responses to exercise testing
J. Mark VanNess, Ph.D.

Lipid Replacement and Antioxidant Therapy for Restoring Mitochondrial Function in Fatiguing Illnesses and Chronic Fatigue Syndrome
Garth Nicolson, Ph.D.

A Randomized Double-blind, Placebo-controlled cross-over Study with Methylphenidate in Sixty Patients with Chronic Fatigue Syndrome
Daniel Blockmans M.D., Ph.D.

 

Clinical Trials Section

Effect of Modafinil on daytime hypersomnia in patients with Chronic Fatigue Syndrome
Dr. Ferran J. García-Fructuoso

 

Epidemiology Section

Self-reported Chronic Fatigue and Timed Loaded Standing in The Gambia and in Belgium
Greta Moorkens, M.D., Ph.D.

 

Fatigue Section

Comparing Heart Rate Variability in Chronic Fatigue Syndrome and Healthy Controls using Commercially available Software
Eleanor Stein MD FRCP(C)

Post-exertional malaise following an exercise challenge
Staci R. Stevens, M.A.

Lactose intolerance and/or fructose malabsorption: a predisposing factor for the development of CFS?
Professor Dr. Pascale De Becker

Genetics / Proteomics Section

Genetics of Chronic Fatigue Syndrome and its subgroups defined by latent class anaylsis
Mangalathu Rajeevan

Expression of MicroRNAs (miRNAs) in Chronic Fatigue Syndrome (CFS)
Jonathan R. Kerr,  BSc, MBBCh, MD, PhD, FRCPath.

 

Viral / Immune Section

The establishment of a National ME Observatory for the UK
Dr. Derek Pheby

Incidence of Chromosomally Integrated HHV-6 (CIHHV-6) in a Cohort of CFS patients with Clonal TCR-g and Lymphoid Malignancies
Judy Mikovits


Gender Aspects of CFS Session
Session Chair: Leonard Jason, Ph.D.
Session Description: Interdisciplinary session: Impact of gender
on mechanisms of illness; gender and methodology issues;  menopause
and CFS/FM, use of sex hormones in treatment
pm
Introductory Overview
Birgitta Evengard, M.D., Ph.D..IACFS Board Member
Chairman Conference Planning Committee, IACFS
Senior Doctor & Professor, Karolinska University Hospital, Stockholm, Sweden

4:00-4:30pm
Gender Aspects of CFS Paper Presentations

Differences Between a Group of CFS Women and a Matched Healthy Control Group in the Cardioventilatory Response to a Maximal and a Supramaximal Test
Dr. Casimiro  Javierre  &  Dr. Andrea Suarez

Considering Gender, Sexuality, and Intimacy in the Care of CFS and FM Patients
Patricia Fennell, MSW, LCSW-R

Evidence for Diastolic Dysfunction in the Chronic Fatigue Syndrome enhanced
by Tilt-Echocardiography: A study of ninety consecutive cases
Paul Cheney, M.D.

4:30-5:00pm
Session Summary: Gender Aspects with a CFS-Perspective

Lucinda Bateman, M.D., IACFS Board Member

Adjunct Clinical Faculty, University of Utah, Department of Internal Medicine, Adjunct Instructor, University of Utah, Family and Preventive Medicine


5:30-6:30pm
Cocktail - Networking Reception


 

IACFS  Banquet

6:30-7:15pm
Meal Service

Dessert Service &
Awards Presentation
7:15-7:40pm
Rudy Perpich Memorial Award

7:40-7:55pm
Junior Investigator Award

7:55-8:00pm
Nelson Gantz Clinician Award

8:00-9:00pm
Panel Discussion: Politics of Women's Health

Moderator: Bob Mayer
                    Journalist

Patricia Ireland, Esq 
Past President, National Organization for Women

Birgitta Evengard, M.D., Ph.D., IACFS Board Member
Chairman Conference Planning Committee, IACFS
Senior Doctor & Professor, Karolinska University Hospital, Stockholm, Sweden

Eleanor Z. Hanna, Ph.D.
Associate Director for Special Projects and Centers, Office of Research on
Women’s Health, Office of the Director, National Institutes of Health

Vivian Pinn, M.D.
Associate Director for Research on Women's Health / Director, Office of Research on Women's Health, National Institutes of Health, (NIH)

Sunday, January 14th

8:00am 
Registration Opens


 

Genetics / Proteomics Session
Session Chair: Kenny De Meirleir, M.D.
Session Description: Integrative session: What we have
learned from other illnesses; how gene arrays can help integrate
multidiscipline data; proteomics and its potential as a clinical tool

8:00-8:30am
Introductory Overview
Suzanne D. Vernon, Ph.D.

8:30-9:45am
Genetics / Proteomics Paper Presentations

Genetic Profiles in Severe Forms of Fibromyalgia and Chronic Fatigue Syndrome
Ferran J. García-Fructuoso, M.D.

Genetic contribution to Chronic Fatigue Syndrome (CFS) and associated pain-
and fatigue- related diagnoses described in a population-based genealogical
resource in Utah
Frederick S. Albright, M.S., Ph.D.

KIR Immunogenetics in CFS Italian Patients
Professor Mariaclara Cuccia

Reduced Levels of Oestrogen receptor {beta} mRNA in Swedish Patients
with Chronic Fatigue Syndrome
Birgitta Evengard, M.D., Ph.D.

Proteomic Biosignature of Chronic Fatigue Syndrome in Cerebrospinal Fluid
James Baraniuk M.D.

CFS Heterogeneity Elucidated via Subspace Clustering
Eric R. Aslakson, M.S.

9:45-10:15am
Session Summary: Genetics / Proteomics with a CFS-Perspective
Jonathan R. Kerr,  BSc, MBBCh, MD, PhD, FRCPath.
Sir Joseph Hotung Clinical Senior Lecturer in Inflammation
Hon. Consultant in Microbiology, St George’s University of London


10:15-10:30am
Break - Visit Posters & Exhibits


 

10:30am
Exhibit Hall and Poster Sessions Conclude


New Methods for Evaluating the Fatigue State Session
Session Co-Chairs:
Hirohiko Kuratsune, M.D., D.Med.Sci.
Professor Yasuyoshi Watanabe

Coordinated by the Japanese Association for Fatigue Sciences

10:30-10:50am
BSpectroscopic diagnosis of chronic fatigue syndrome by visible and near-
infrared spectroscopy in serum samples

Akikazu Sakudo, Ph.D.
Research Associate, Department of Virology, Center for Infectious Disease Control,
Research Institute for Microbial Diseases, Osaka University, Department of Physiology,
Osaka City University Graduate School of Medicine, Osaka, Japan

10:50-11:10am
Enhancement of herpes virus 6 (HHV-6) and herpesvirus 7
(HHV-7) reactivation in saliva during the fatigue state
Yoshitaka Kajimoto, M.D.
President and CEO, Soiken, Inc.
Affiliate Professor of Medicine, Wakayama Medical University

11:10-11:30am
Application of DNA chip for Fatigue Assessment
Kazuhito Rokutan, M.D., Ph.D.
Professor & Director, Department of Stress Science,
Institute of Health Biosciences, The University of Tokushima Graduate
School, Tokushima, Japan


 

11:30-12:30pm
Lunch Break


Viral and Immune Interactions and Health Session

Session Co-Chairs: Dharam V. Ablashi, DVM, MS, Dip. Bact.
                                  Lee Meisel, M.D., J.D.
Session Description: Chronic active viral infection in CFS; diagnostic methodology
issues; sub-grouping by viral status; impact on immune and neurological regulation;
impact of antiviral treatment on outcome.

Coordinated by the HHV-6 Foundation

12:30-1:00pm
Overview of EBV, Stress and Viral Latency in CFS
Ronald Glaser, Ph.D.
Director, Institute for Behavioral Medicine & Professor, Molecular Virology, Immunology & Medical Genetics, Ohio State University, Medical Center.

1:00-1:20pm
Overview of HHV-6 in CFS and Diagnostic Assays for Detecting Chronic Active HHV-6 and EBV
Dharam V. Ablashi, DVM, MS, Dip. Bact.
Co-Founder, Past President and Treasurer, IACFS
Co-Founder, International Epstein-Barr Virus Association
Scientific Director, HHV-6 Foundation

1:20-1:50pm
Immune Paper Presentations

Immunological Comparison of Gulf War Illness and CFS
Mary Ann Fletcher, Ph.D.

Elevated Proinflammatory IL-6 in Patients with Chronic Fatigue Syndrome
Brian M. Gurbaxani, Ph.D.

1:50-3:05pm
Viral Paper Presentations

The HHV6 U45 protein is not a functional dUTPase, but it does induce immune dysregulation similar to the EBV-encoded dUTPase
Marshall V. Williams, Ph.D.

Incidence of HHV-6 and EBV Infection in Chronic Fatigue Syndrome Patients
Susan Levine, M.D.

HHV-6 and HHV-7 Infection in Chronic Fatigue Syndrome
Modra Murovska, Ph.D.

Chronic Fatigue Syndrome is Associated with Persistent Enterovirus Infection of the Stomach
John K. Chia, M.D.

Chronic Bacterial Co-Infections in CFS and CFS Patients Subsequently Diagnosed with Lyme Disease
Garth L. Nicolson, Ph.D.

3:05-3:30 pm
HHV-6 Biology, Viruses and Immunology in CFS
Anthony L. Komaroff, M.D.
Professor of Medicine, Harvard Medical School


3:30-3:45 pm
Closing Remarks
Anthony L. Komaroff, M.D.
Professor of Medicine, Harvard Medical School


3:45pm
General Conference Sessions Concludes


3:45-4:00pm
Break


4:00-5:30pm
Post Conference Workshop: Infections in CFS
Session Description: Non CME bonus session designed
for investigators developing protocols that integrate viral and
immune measures or antiviral or immunomodulatory strategies

 

Session Co-Chairs: Ronald Glaser, Ph.D.
                                  Dharam V. Ablashi, DVM. MS, Dip Bact
4:00 – 4:45pm Basic Science Panel Discussion
Ronald Glaser, Ph.D.
Dharam V. Ablashi, DVM, MS, Dip. Bact.  
John K. Chia, M.D.  
Yoshitaka Kajimoto, M.D.  
Jonathan R Kerr  BSc, MBBCh, MD, PhD, FRCPath.  
Constance Knox, Ph.D.
Modra Murovska, Ph.D.
Garth L. Nicolson, M.D.
Marshall Williams, Ph.D.


Session Co-Chairs: Jose G. Montoya, M.D.
                                  Daniel Peterson, M.D.
4:45 - 5:30pm Clinical Science Panel Discussion
Jose G. Montoya, M.D.
Dan Peterson, M.D.
Joe Brewer, M.D.
Nancy Klimas, M.D.
Anthony L. Komaroff, M.D.  
Susan Levine, M.D.  
Martin Lerner, M.D.